Thursday, 11th February

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Speakers

2:00PM - 2:10PM

2:10PM - 4:00PM

Thursday, 11th February

Not available at time of printing - Ben Solomon
Understanding the mechanisms of sensitivity and resistance to targeted and immune therapies in lung cancer - Kwok-Kin Wong
Human lung basal cells are activated by cigarette smoke and are the putative cell of origin of lung squamous cell carcinoma - Clare E Weeden
Not available at time of printing - Charles Swanton

4:00PM - 4:30PM

Thursday, 11th February

Exhibition Hall

4:30PM - 6:10PM

Thursday, 11th February

Enhancer templated RNAs as predictors of therapeutic response to epigenetic therapy - Ron Firestein
Synergistic action of anti-microtubule and anti-tropomyosin agents on neuroblastoma. - Ashleigh Swain
Mechanisms of sensitivity and resistance to epigenetic therapies in AML - Mark Dawson
Not available at time of printing - Hakim Djaballah

6:15PM - 7:30PM

Thursday, 11th February

Mantra Lawn Area

7:30PM - 10:00PM

Thursday, 11th February

Exhibition Hall

SMCHD1 regulates epithelial-to-mesenchymal transition in 5-FU drug resistant colorectal cancer cells - Nidhi Abraham
TRXE-009-1, an investigational small molecule, significantly inhibits tumour growth and extends survival in vivo - Eleanor I Ager
Investigating the role of Mcl-1 in lung development and lung cancer - Casey Ah-Cann
MITF regulates EMT and drives subcompartment-specific distribution of differentially cycling melanoma cells - Farzana Ahmed
Hypoxia and colorectal cancer stem cells - Reem ALHulais
Modelling the contribution of Signal transducer and activator of transcription 3 (STAT3) to tumour growth and maintenance - Mariah M.A. Alorro
Targeting MDMX to treat wt-p53/mutant p53 expressing Breast Cancer - Panimaya Jeffreena Miranda Alphonse Miranda
Identification of Novel Therapeutic Agents and Biomarkers in Glioblastoma Multiforme - Zammam Areeb
The ACRF Drug Discovery Centre: An early-stage drug discovery facility - Greg M Arndt
FGFR1 inhibition in patient-derived xenograft models of lung squamous cell carcinoma - Marie-Liesse Asselin-Labat
Quiescence as a marker of treatment resistance and malignancy in GBM - Ryan J Atkins
Age-related increase in mTOR activity contributes to the pathogenesis of ovarian cancer - Preety Bajwa
Characterising the molecular function of Inhibitor of Differentiation 4 in basal-like breast cancer - Laura Baker
Tumour cell secreted immunoregulatory cytokines associated with prostate cancer bone metastasis - Nikola Baschuk
Evaluation of Melanocytic, Melanoma, and Stem Cell Marker Expression in Primary Uveal Melanoma for the Improvement of Immunomagnetic Circulating Tumour Cell Capture - Aaron Beasley
Prevention of MAPK pathway-driven proliferation of RAS-mutated colorectal cancers with new generation BRAF inhibitors - Andreas Behren
Characterisation of ADAMTS-15: a potential tumour suppressor gene in prostate cancer - Marley J Binder
Exosomes transfer chemotherapeutic drug resistance between colorectal cancer cells - Stephanie Boukouris
Induced expression of the immune suppressor Programmed Death Ligand 1 in breast cancer - Natasha Brockwell
Identification of dormant prostate cancer cells in the skeleton in vivo and ex vivo - Niall M Byrne
The role of planar cell polarity genes in the progression of prostate cancer - Benjamin Caldwell
A novel role for Top2a as a mediator of resistance to ribosomal DNA transcription inhibition - Don P Cameron
Exploring the Mechanism of MYB Transcriptional Regulation in Myeloid Leukaemia - Lu Cao
Novel approaches to targeting the tumour-stroma coalition in triple negative breast cancers - Aurélie Cazet
A genome-wide RNAi screen for bypass of AKT-induced senescence - Keefe T Chan
Utilising miR-210 to sensitise malignant pleural mesothelioma to cisplatin and gemcitabine - Yuen Yee Cheng
Functional Analysis of TP53 Mutants in the LNCaP Prostate Cancer Cell Line - Michael Clarkson
The novel anti-tropomyosin drug ATM-3507 enhances the activity of standard chemotherapy for prostate cancer in pre-clinical models - Adam Cooper
Investigating the role of Histidine metabolism in brain tumours in Drosophila melanogaster - Olivia Costas
ABT-737 enhances the effect of doxorubicin on T47D breast cancer cells through caspase independent cell death - Rebecca Dalle Nogare
Understanding breast tumourigenesis through 3 and 4-dimensional imaging - Caleb Dawson
Par3 in haematopoiesis and leukaemogenesis - Alysha Dew
A comprehensive and systematic analysis of miRNA function in neuroblastoma - Eoin Dodson
Characterization and comparison of spatio-temporally separated tumor immunomes in melanoma patients - Xuelin Dou
Seromic profiling of melanoma patients using a custom protein microarray platform - Jessica Duarte
THE ROLE OF STROMAL STEFIN A IN PREVENTING BREAST CANCER INVASION - Hendrika M Duivenvoorden
Deciphering intratumour heterogeneity by proliferative cell profiling - Berwini B Endaya
Exploiting the cell cycle to improve treatment efficacy in childhood brain tumours - Raelene Endersby
In vitro drug sensitivity testing of high risk childhood cancer patient cells for potential new drug treatments - Tim W Failes
TrkA is overexpressed and is a potential adjunct therapeutic target in HER2-positive breast cancers - Sam Faulkner
Primary and regionally metastatic melanomas contain high proportions of cells with tumorigenic and metastatic potential - Clare G Fedele
Knockdown of p120ctn induces mesenchymal-to-epithelial transition and activates Wnt signalling pathway - Pamali Fonseka
Using a Gene Expression Signature of TGFβ-induced EMT to Predict Cancer Cell Lines and Breast Cancer Patients with Active TGFβ Signalling - Momeneh Foroutan
Novel immunotherapy approaches in luminal ER+ breast cancer. - David Gallego Ortega
E6AP is a novel regulator of the INK4/ARF locus: implications for Non-Small Cell Lung Cancer - Cristina Gamell
Exome sequencing reveals multiregional variation in cutaneous squamous cell carcinoma and surrounding photodamaged skin - Orla Gannon
PI3K inhibitors enhance the efficacy of FGFR inhibitor in FGFR2 mutant endometrial cancers - Xinyan Geng
Targeting the DNA damage response pathway to identify novel combination treatments for medulloblastoma - Courtney George
Understanding the interaction between brain tumours and the immune system - Tenielle George
Forced expression of miR-101a reverses the epigenetic landscape and genetic events in AML stem cells - Estrella Gonzales-Aloy
The role of invadopodia in the metastatic potential of colorectal cancers - Justin W Gourlay
Non-invasive detection of treatment response and acquired resistance in patients with metastatic melanoma - Elin Gray
Exploring the Involvement of E6AP in Prostate Cancer Using a combined Proteomic and Transcriptomic Approach - Twishi Gulati
Differentially expressed microRNAs in circulating leucocytes from patients with locally advanced rectal cancer - Benjamin H.L Harris
Development of a national bioresource of patient derived xenografts (PDX) of primary and metastatic breast cancer, for the improvement of preclinical modeling and biomarker discovery - Kate Harvey
Exploring the Role of Endothelium in the Tumour Response to Anti-Angiogenic Therapy - Michael He
The truncation, optimization and functionalization of a DNA chemical antibody targeting EpCAM for the delivery of a common chemotherapeutic agent - Justin L Henri
Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease and drug-dependent dynamic regulation of cell-cell junctions in live tissue - David Herrmann
Paradoxical in vivo effect of Vismodegib on a high-grade serous ovarian cancer patient-derived xenograft over-expressing the Hedgehog pathway - Gwo Yaw Ho
Unravelling Regulatory Transcriptional Networks Governing Mammary Gland Lineage Commitment - Holly Holliday
Identification of membrane proteins associated with metastatic progression in breast cancer - Pauline Huang
Csk-binding protein controls red blood cell development via regulation of Lyn tyrosine kinase activity - Evan Ingley
An antibody that selectively binds the active ADAM10 metalloprotease and inhibits notch signalling in tumours - Peter Janes
Investigating the role of heparanase in breast cancer progression using the PyMT-MMTV mouse model - Krish M Jayatilleke
Combination treatment of colorectal cancer cells with MAPK and HDAC inhibitors enhances differentiation induction - Laura J Jenkins
Short interfering RNA induced generation and translation of stable 5’ mRNA cleavage intermediates - Luqman Jubair
Tumour associated versican (V1) alters the physiological properties of macrophages - Adrian Kaczmarek
Effects of EphB4 Receptor Expression on Colorectal Cancer Cell Behaviour, Tumour Growth and Vascularisation - Elif Kadife
Targeting glutamine metabolism to improve the efficacy of rDNA transcription inhibitor CX-5461 in MYC-driven B cell lymphoma - Jian Kang
Bumetanide derivatives AqB007 and AqB011 are selective blockers of Aquaporin 1 ion channel conductance and slow cancer cell migration - Mohamad Mr Kourghi
Proteomic phenotyping of patient-derived melanoma cancer cell lines correlates with MEK inhibitor resistance independent of genotype and predicts poor patient outcome - Christoph Krisp
RNA-Seq of localized prostate cancer treated with “super castration” therapy - Natalie J Kurganovs
Defining changes in the translation profiles of cancer cells in response to therapies targeting the ribosome - Eric P Kusnadi
Integrative Analysis of Invasive Lobular Carcinoma - Samir Lal
Chronic stress remodels tumor lymphatic vasculature to promote metastatic dissemination - Caroline P Le
Direct inhibition of STAT signaling by platinum drugs contributes to their anti-cancer activity - Willem J Lesterhuis
Identification and characterization of a putative tumor suppressor gene AKR7A3 in hepatocellular carcinoma. - Yan Li
Exosomes secreted by PI3K signaling pathway activated colorectal cancer cells mediate cell proliferation - Michael Liem
Long-term impact of ionizing radiation on skeletal muscle in mice – toward an understanding of metabolic syndrome - Nadia Maria Lopes Amorim
Assessing FAK activity and therapeutic targeting in the context of pancreatic cancer using advanced imaging techniques - Morghan C Lucas
Candidate genes predisposing to familial appendiceal mucinous neoplasms with pseudomyxoma peritonei - Mei Sim Lung
Co-targeting PAR1 and JNK signalling to eradicate leukaemic stem cells - Jennifer Lynch
STAT3 in Medulloblastoma - Christine L White
Redirecting immune subsets through genetic manipulation for enhancing adoptive immunotherapy - Carmen SM Yong
AC220 priming inhibits chemotherapy-induced myelosuppression - Samuel Taylor
Extracellular vesicles activate Wnt signaling pathway by the transfer of mutated β-catenin - Hina Kalra
Screening for activity against a human Acute Monocytic Leukemia cell line of compounds isolated from a South Australian Marine sponge. - Salamah Alamri
Stability After Storage of a Gold Nanoparticle-Docetaxel Conjugate Assessed by Breast Cancer Cell Killing - Nada Ahmed Alzahrani
Mechanisms of metastasis and outgrowth from dormancy in bone-metastatic prostate cancer - Katie Owen

Friday →

Thursday, 11th February 28th Lorne Cancer Conference 2016

Welcome

Session 1 - Lung Cancer

Afternoon Tea

Session 2: Therapeutics

Welcome Bazaar

Poster Session 1